ROS-Nitric Oxide Pathway Reagents and Kits
Abcam Histone H3 (di-methyl K9) Quantification Kit (Colorimetric).
Histone H3 (di-methyl K9) Quantification Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Histone H3 (mono-methyl K4) Quantification Kit (Colorimetric).
Histone H3 (mono-methyl K4) Quantification Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Histone H4 (tri-methyl K20) Quantification Kit (Fluorometric).
Histone H4 (tri-methyl K20) Quantification Kit (Fluorometric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Histone H3 (di-methyl K36) Quantification Kit (Colorimetric).
Histone H3 (di-methyl K36) Quantification Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Histone H3 (pan-methyl K27) Quantification Kit (Colorimetric).
Histone H3 (pan-methyl K27) Quantification Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Histone H3 (mono-methyl K27) Quantification Kit (Colorimetric).
Histone H3 (mono-methyl K27) Quantification Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Histone H3 (di-methyl K9) Quantification Kit (Colorimetric).
Histone H3 (di-methyl K9) Quantification Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Histone H3 (tri-methyl K4) Quantification Kit (Colorimetric).
Histone H3 (tri-methyl K4) Quantification Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Caryophylen oxIde 1g
An irreversible FGFR inhibitor (IC50s 3 09 4 3 27 and 45 3 nM for FGFR1 FGFR2 FGFR3 and FGFR4 respectively) inhibits cell proliferation of transformed Ba/F3 cell lines and demonstrates antiproliferative activity in cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2
Enzo Life Sciences L-NMMA . monoacetate (25mg). CAS: 53308-83-1
Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg). Alternative name: NG-Monomethyl-L-arginine . monoacetate. Formula: C7H16N4O2 . CH3COOH. MW: 188.2 . 60.1. Purity: ≥99% (TLC). Solubility: Soluble in water, 100% ethanol (1mg/ml) or DMSO (0.25mg/ml). Long Term Storage: +4°C.
Enzo Life Sciences BAY 41-2272 (5mg). CAS: 256376-24-6
NO-independent activator of soluble guanylyl cyclase (sGC). Activates both isoforms α1β1 and α1β2 of sGC. While the related compound YC-1 (ALX-420-025) also acts as a non-specific phosphodiesterase inhibitor, BAY 41-2272 has no effect on phosphodiesterases. Stimulation of sGC is not blocked by high concentrations of NO scavengers (e.g. PTIO, ALX-430-007) and the combination of BAY 41-2272 with the NO donor DEA NONOate (ALX-430-034) potentiates the activation of sGC. Although BAY 41-2272 alone is not as strong a stimulator of sGC as NO, concentrations as low as 10-100nM stimulate sGC to a level that would be expected to cause biologically important increases in cGMP. Alternative name: 3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine. Purity: ≥98% (HPLC). Appearance: White to off-white needles. Solubility: Soluble in DMSO, dichloromethane, 100% ethanol or 2-pyrrolidone; practically insoluble in water.
Enzo Life Sciences DETA NONOate (5mg). CAS: 146724-94-9
Nitric oxide (NO) donor. Induces apoptosis in macrophages. The half-life time of DETA NONOate is 20 hours at 37°C and 56 hours at 22-25°C in 0.1M phosphate buffer, pH 7.4. Decomposition of NONOates is nearly instantaneous at pH 5.0. DETA NONOate liberates 2 mol of NO per mol of parent compound. Alternative name: NOC-18, DETA/NO, (Z)-1-[2-(2-Aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate, 3 3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene, 2 2'-(Hydroxynitrosohydrazino)bis-ethanamine. Purity: ≥97% (1H-NMR). Solubility: Soluble in water or ethanol. Long Term Storage: -80°C.
Abcam Nitric Oxide Assay Kit (Colorimetric)
Nitric Oxide Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Bioassay Systems QuantiChrom™ Nitric Oxide Assay Kit. For quantitative determination of nitric oxide (nitrate/nitrite) and evaluation of drug effects on its metabolism.
For quantitative determination of nitric oxide (nitrate/nitrite) and evaluation of drug effects on its metabolism. Key Features: Sensitive and accurate. Detection range 0.6 - 200 µM in 96-well plate. Rapid and reliable. Using an optimized VCl3 reagent, the time required for reduction of nitrate (NO3-) to nitrite (NO2-) is reduced to 10 min at 60°C. Simple and high-throughput. The procedure involves mixing sample with three reagents, incubation for 10 min at 60°C and reading the optical density. Can be readily automated to measure thousands of samples per day. Method: OD540nm. Samples: Plasma, serum, urine, tissue/cells and foods. Species: All. Procedure: Assay takes 40 min. Kit size: 100 tests. Detection limit: 0.6 µM.
